Comparison of the 2 detection methods of sars covid 2 Sep 29, 2020



Nucleic Acid Testing


Antigen Detection

Detection of samples

Nasopharyngeal nylon flocked swab

or oropharyngeal nylon flocked swab, sputum

nasopharyngeal nylon flocked swab or anterior nasal nylon flocked swab, Sputum or pulmonary

Detection target


Genes: RdRp, Orflab, and E 、N 、S

Structural proteins : S, N, M, and E

Detection window period

Early stage of infection, until eliminate the virus after recovery

Early stage of infection, until eliminate the virus after recovery


Detection Time

2-4 Hours

Within 15 minutes

Detection requirement

At least BSL-2 laboratory

No special requirements





Advantages & Disadvantages


Advantages: High sensitivity,high specificity ;

Disadvantages: Time-consuming and labor intensive

Advantages: easy operation, rapid test time, low cost, the environmental requirements are not high ;

Disadvantages: Samples with low levels of virus may not be detected. It is best to use nucleic acid detection methods to check and confirm to avoid misjudgment.

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